Two sample MR report
HLA-C_CD4+ T Cell against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.1669145 | 0.1474012 | 0.4605282 |
| Weighted median | 3 | -0.0381272 | 0.0201132 | 0.0580085 |
| Inverse variance weighted | 3 | -0.0525777 | 0.0159906 | 0.0010089 |
| Simple mode | 3 | -0.0319653 | 0.0263805 | 0.3493569 |
| Weighted mode | 3 | -0.0319653 | 0.0276295 | 0.3668139 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0005746 | 1 | 0.9808754 |
| Inverse variance weighted | 2.2414637 | 2 | 0.3260411 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1774749 | 0.1185569 | 0.3749304 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.59e-05 | 0 | TRUE | 0.5756694 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
